Quant M3 Publications (2008- )
- Dynamin-Related Protein 1-Dependent Mitochondrial Fission Changes in the Dorsal Vagal Complex Regulate Insulin Action. Filippi BM, Abraham MA, Silva PN, Rasti M, LaPierre MP, Bauer PV, Rocheleau JV, Lam TK. Cell Rep. 2017 Mar 7;18(10):2301-2309. doi: 10.1016/j.celrep.2017.02.035.
- Clarifying intact 3D tissues on a microfluidic chip for high-throughput structural analysis. Chen YY, Silva PN, Syed AM, Sindhwani S, Rocheleau JV, Chan WC. Proc Natl Acad Sci USA. 2016 Dec 27;113(52):14915-14920. doi: 10.1073/pnas.1609569114.
- Single-Molecule Analysis of the Supramolecular Organization of the M2 Muscarinic Receptor and the Gαi1 Protein. Shivnaraine RV, Fernandes DD, Ji H, Li Y, Kelly B, Zhang Z, Han YR, Huang F, Sankar KS, Dubins DN, Rocheleau JV, Wells JW, Gradinaru CC. J Am Chem Soc. 2016 Sep 14;138(36):11583-98. doi: 10.1021/jacs.6b04032.
- Highly efficient adenoviral transduction of pancreatic islets using a microfluidic device. Silva PN, Atto Z, Regeenes R, Tufa U, Chen YY, Chan WC, Volchuk A, Kilkenny DM, Rocheleau JV. Lab Chip. 2016 Aug 7;16(15):2921-34. doi: 10.1039/c6lc00345a.
- Allosteric modulation in monomers and oligomers of a G protein-coupled receptor. Shivnaraine RV, Kelly B, Sankar KS, Redka DS, Han YR, Huang F, Elmslie G, Pinto D, Li Y, Rocheleau JV, Gradinaru CC, Ellis J, Wells JW. Elife. 2016 May 6;5. pii: e11685. doi: 10.7554/eLife.11685.
- The FGF21 Receptor Signaling Complex: Klothoβ, FGFR1c, and Other Regulatory Interactions. Kilkenny DM, Rocheleau JV. Vitam Horm. 2016;101:17-58. doi: 10.1016/bs.vh.2016.02.008.
- Tailoring nanoparticle designs to target cancer based on tumor pathophysiology. Sykes EA, Dai Q, Sarsons CD, Chen J, Rocheleau JV, Hwang DM, Zheng G, Cramb DT, Rinker KD, Chan WC. Proc Natl Acad Sci USA. 2016 Mar 1;113(9):E1142-51. doi: 10.1073/pnas.1521265113.
- Jagn1 Is Induced in Response to ER Stress and Regulates Proinsulin Biosynthesis. Nosak C, Silva PN, Sollazzo P, Moon KM, Odisho T, Foster LJ, Rocheleau JV, Volchuk A. PLoS One. 2016 Feb 16; 11(2):e0149177. doi: 10.1371/journal.pone.0149177.
- Apollo-NADP(+): a spectrally tunable family of genetically encoded sensors for NADP(+). Cameron WD, Bui CV, Hutchinson A, Loppnau P, Gräslund S, Rocheleau JV. Nat Methods. 2016 Apr; 13(4):352-8. doi: 10.1038/nmeth.3764.
- Increased pressure alters plasma membrane dynamics and renders acute myeloid leukemia cells resistant to daunorubicin. Nirmalanandhan VS, Hurren R, Cameron WD, Gronda M, Shamas-Din A, You L, Minden MD, Rocheleau JV, Schimmer AD. Haematologica. 2015 Oct; 100(10):e406-8. doi: 10.3324/haematol.2015.129866.
- Fu A, Robitaille K, Faubert B, Reeks C, Dai XQ, Hardy AB, Sankar KS, Ogrel S, Al-Dirbashi OY, Rocheleau JV, Wheeler MB, MacDonald PE, Jones R, Screaton RA. LKB1 couples glucose metabolism to insulin secretion in mice. Diabetologia. 2015 Apr 16.
- Albanese A, Lam AK, Sykes EA, Rocheleau JV, Chan WC. Tumour-on-a-chip provides an optical window into nanoparticle tissue transport. Nat Commun. 2013 Nov 1;4:2718.
- Silva PN, Green BJ, Altamentova SM, Rocheleau JV. A microfluidic device designed to induce media flow throughout pancreatic islets while limiting shear-induced damage. Lab Chip. 2013 Oct 15;13(22):4374-84.
- Patel PC, Lee HS, Ming AY, Rath A, Deber CM, Yip CM, Rocheleau JV, Gray-Owen SD. Inside-out Signaling Promotes Dynamic Changes in the Carcinoembryonic Antigen-related Cellular Adhesion Molecule 1 (CEACAM1) Oligomeric State to Control Its Cell Adhesion Properties. J Biol Chem. 2013 Oct 11;288(41):29654-69.
- Silva PN, Altamentova SM, Kilkenny DM, Rocheleau JV. Fibroblast growth factor receptor like-1 (FGFRL1) interacts with SHP-1 phosphatase at insulin secretory granules and induces beta-cell ERK1/2 protein activation. J Biol Chem. 2013 Jun 14;288(24):17859-70.
- Sun MY, Yoo E, Green BJ, Altamentova SM, Kilkenny DM, Rocheleau JV. Autofluorescence imaging of living pancreatic islets reveals fibroblast growth factor-21 (FGF21)-induced metabolism. Biophys J. 2012 Dec 5;103(11):2379-88.
- Lam AK, Silva PN, Altamentova SM, Rocheleau JV. Quantitative imaging of electron transfer flavoprotein autofluorescence reveals the dynamics of lipid partitioning in living pancreatic islets. Integr Biol (Camb). 2012 Aug;4(8):838-46.
- Ming AY, Yoo E, Vorontsov EN, Altamentova SM, Kilkenny DM, Rocheleau JV. Dynamics and Distribution of Klothoβ (KLB) and fibroblast growth factor receptor-1 (FGFR1) in living cells reveal the fibroblast growth factor-21 (FGF21)-induced receptor complex. J Biol Chem. 2012 Jun 8;287(24):19997-20006.
- Sankar KS, Green BJ, Crocker AR, Verity JE, Altamentova SM, Rocheleau JV. Culturing pancreatic islets in microfluidic flow enhances morphology of the associated endothelial cells. PLoS One. 2011;6(9):e24904.
- Martin MD, Kremers GJ, Short KW, Rocheleau JV, Xu L, Piston DW, Matrisian LM, Gorden DL. Rapid extravasation and establishment of breast cancer micrometastases in the liver microenvironment. Mol Cancer Res. 2010 Oct;8(10):1319-27.
- Vellanki RN, Zhang L, Guney MA, Rocheleau JV, Gannon M, Volchuk A. OASIS/CREB3L1 induces expression of genes involved in extracellular matrix production but not classical endoplasmic reticulum stress response genes in pancreatic beta-cells. Endocrinology. 2010 Sep;151(9):4146-57.
- Easley CJ, Rocheleau JV, Head WS, Piston DW. Quantitative measurement of zinc secretion from pancreatic islets with high temporal resolution using droplet-based microfluidics. Anal Chem. 2009 Nov 1;81(21):9086-95.
- Rocheleau JV, Piston DW. Chapter 4: Combining microfluidics and quantitative fluorescence microscopy to examine pancreatic islet molecular physiology. Methods Cell Biol. 2008;89:71-92.
- Kilkenny DM, Rocheleau JV. Fibroblast growth factor receptor-1 signaling in pancreatic islet beta-cells is modulated by the extracellular matrix. Mol Endocrinol. 2008 Jan;22(1):196-205.